This is the Linux app named DESN whose latest release can be downloaded as DEN_1.0.tar.gz. It can be run online in the free hosting provider OnWorks for workstations.
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DESN
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DESCRIPTION
Living cells are complex, dynamic, self-regulatory, interactive systems, showing differential states across time and space. Complexity of cellular systems is highlighted with the multi-layered regulatory mechanisms involving the interactions between bio-molecules (such as DNA, RNA, mi-RNA and proteins). These interactions are analyzed in the form of static networks. Likewise, number of experimental techniques like microarray, RNASeq allows quantification of cellular dynamics and aid in discerning differential gene expression across diverse conditions. Computational biology is in need of methods for integration of static networks and gene expression data, since it provides interesting insights into the dynamics of biological systems. DEN is an R/Bioconductor based package designed to assemble different types of human bio-molecular interactions as a complete interactome and contains functions to extract dynamic active networks by integration of gene expression data.
Audience
Science/Research
User interface
Console/Terminal
Programming Language
S/R
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/desn/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
