This is the command mssstest that can be run in the OnWorks free hosting provider using one of our multiple free online workstations such as Ubuntu Online, Fedora Online, Windows online emulator or MAC OS online emulator
PROGRAM:
NAME
mssstest - Normalisationo of disease scores - originally developed for the EDSS for
Multiple Sclerosis
SYNOPSIS
mssstest
DESCRIPTION
Suppose one is interested in determining whether the genotype at some locus of interest
affects the rate of progression of disease of people with Multiple Sclerosis (MS). One
method would be to calculate the mean EDSS score in patients with each of the genotypes
and test whether they are significantly different. However, this approach is inefficient
if patients have their EDSS assessed at different durations of disease, as patients who
have had MS longer typically have higher EDSS scores regardless of their genotype. By
adjusting for duration, a more powerful test can be developed.
MSSStest is a program for implementing the method described in the article The Multiple
Sclerosis Severity Score. R. Roxburgh S. Seaman et al. (2004), accepted for publication by
Neurology. It calculates MSSS scores and uses these scores to test for differences between
disease progression rates in different groups defined by genotype at some locus.
To use the program first copy the table of disease scores to the current directory. You
are expected to use the EDSS scores provided by the authors.
OPTIONS
The program does not accept options, it should, though. The output goes to the files
"msss.out" and "indivmsss.out".
Use mssstest online using onworks.net services
