This is the Windows app named diauxic growth model ensemble whose latest release can be downloaded as ensemble_diauxic_growth_fitted_models.zip. It can be run online in the free hosting provider OnWorks for workstations.
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diauxic growth model ensemble
DESCRIPTION
An ensemble of mathematical model is presented that all show diauxic growth behaviour of a bacterial culture.
Carbon catabolite repression (CCR) is the main mechanism controlling
carbohydrate uptake in bacteria, and therefore also controlling
whether or not different carbon sources are metabolized in parallel or
sequentially. Although described as a paradigm of the regulation of
bacterial metabolism, the underlying mechanisms remain controversial.
The models in the ensemble can be categorized according to regulatory,
stoichiometric, and physiological constraints and differ from each
other on only a single aspect. We distinguish four groups of models:
(1) flux balance models that only define reaction kinetics for
substrate uptake and by-product excretion, (2) kinetic models without
and (3) kinetic models with regulation on the metabolic and/or genetic
level, and (4) resource allocation models.
Audience
Education
Programming Language
MATLAB
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/diauxic-growth-model-ensemble/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
