This is the Windows app named Glycosylation Microviewer whose latest release can be downloaded as GMV1.01b-release.rar. It can be run online in the free hosting provider OnWorks for workstations.
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SCREENSHOTS
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Glycosylation Microviewer
DESCRIPTION
Glycosylation Microviewer is an application that create N-linked glycosylation raction network. The model used in the application is based on two significant papers: 1.1997 Pablo Umana, James E.Bailey A Mathematical Model of N-linked Glycoform Biosynthesis. 2.2005 Frederick J.Krambeck, Michael J.Betenbaugh A Mathematical Model of N-linked Glycosylation.
The application allow to simulate the network in dynamic form with various ODE solvers(Euler, Runge-Kutta etc). Genetic Algorithm is used to adjust the kinetic parameters of Michaelis-Menten equations in glycosylation reaction network. A dynamic plot is supplied to show the value of mole amout and mole fraction of various glycoform.
Thanks to Alexey Balakin and Alessandro Presta. Alexey Balakin supply mathgl(https://sourceforge.net/projects/mathgl) that make the implementation of dynamic plot in this application easily. Alessandro Presta supply fga(https://sourceforge.net/projects/fga) that provide a powerful use of GA.
Audience
Science/Research
User interface
Win32 (MS Windows)
Programming Language
C++
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/gmv/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
