This is the Linux app named GenNon-h to run in Linux online whose latest release can be downloaded as GenNonH_share.zip. It can be run online in the free hosting provider OnWorks for workstations.
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GenNon-h to run in Linux online
DESCRIPTION
A number of software packages are available togenerate DNA MSAs evolved under
continuous-time Markov processes on phylogenetic trees. On the other hand,
methods of simulating the DNA MSA directly from the transition matrices
do not exist. Moreover, existing software restricts to
the time-reversible models and it is not optimized to
generate nonhomogeneous data (i.e. placing distinct substitution rates at different lineages).
GenNon-H is the first package designed to generate multiple sequence alignments under
the discrete-time Markov processes on phylogenetic trees, which samples directly from the transition matrices.
Based on the input model and a
phylogenetic tree in the Newick format (with branch lengths measured
as the expected number of substitutions per site), the
algorithm produces DNA alignments of desired length.
GenNon-H is a collaborative project described at http://genome.crg.es/cgi-bin/phylo_mod_sel/AlgGenNonH.pl.
Programming Language
C++
This is an application that can also be fetched from https://sourceforge.net/projects/gennonh/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
