This is the Linux app named MultiTrans whose latest release can be downloaded as MultiTrans.zip. It can be run online in the free hosting provider OnWorks for workstations.
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MultiTrans
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DESCRIPTION
Multiple hypothesis testing is an essential step in GWAS analysis. Although the use of 5 × 10-8 has predominated human GWAS, the correct per-marker threshold differs as a function of species, marker densities, genetic relatedness, and trait heritability. However, no previous multiple testing correction methods can comprehensively account for these factors; therefore, these methods are not applicable for linear mixed models. MultiTrans is an efficient and accurate multiple testing correction approach for linear mixed models. Our method performs a unique transformation of genotype data to account for genetic relatedness and heritability under linear mixed models, as well as to efficiently utilize the multivariate normal distribution.This is an application that can also be fetched from https://sourceforge.net/projects/multitrans/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
