This is the Windows app named GMcloser whose latest release can be downloaded as GMcloser-1.6.2.tar.gz. It can be run online in the free hosting provider OnWorks for workstations.
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GMcloser
DESCRIPTION:
GMcloser fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets.An accompanied package, GMvalue, is a tool to determine misassembly sites in contigs and scaffolds. Unlike other related tools, GMvalue can define misassembly categories with several options, and can be applied to assemblies of a large size genome. By using the -e option, GMvalue also generates error-free assemblies by splitting or correcting misassembles.
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