This is the Windows app named PingPongPro whose latest release can be downloaded as pingpongpro-v1.0-windows64.zip. It can be run online in the free hosting provider OnWorks for workstations.
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PingPongPro
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DESCRIPTION
IMPORTANT NOTE: This project has been migrated to GitHub and is no longer maintained here. Please refer to:
https://github.com/suhrig/pingpongpro
Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs, predominantly active in the germ line. There, they limit the detrimental effect of transposons on the genome. They do so by forming a complex with Piwi proteins. The complex binds and then cleaves mRNA molecules of active transposons. The resulting mRNA fragments induce the production of more piRNAs, thus reinforcing the anti-transposon response in a feed-forward loop called the "ping-pong cycle".
A key question in ping-pong cycle research is identification of piRNAs which are amplified through the cycle. PingPongPro is a command-line tool for detecting ping-pong cycle activity in piRNA-Seq data.
PingPongPro was developed at the Institute of Molecular Biology gGmbH in Mainz.
Audience
Science/Research
User interface
Command-line
Programming Language
C++
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/pingpongpro/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
