This is the Linux app named The Protein Similarity Network whose latest release can be downloaded as PSIN_0.0.2.tar.gz. It can be run online in the free hosting provider OnWorks for workstations.
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The Protein Similarity Network
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DESCRIPTION
This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity.
We found that this network is particularly useful to distinguish approved from problematic drug-targets.
Here you also find the complete set of programs and datasets we used for this purpose.
Free to help further test and develop this project. Your help and expertise are much appreciated !
If you have any questions, please do not hesitate to contact us in the forum or by email.
Please see the original manuscript:
Lopes, TJS, et al. (2015) - "Identifying problematic drugs based on the characteristics of their targets" - Frontiers in Pharmacology doi: 10.3389/fphar.2015.00186
Audience
Healthcare Industry, Science/Research, Advanced End Users
Programming Language
Perl, Java, S/R
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/psin/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
